Azelaic Acid is a naturally occurring chemical belonging to the class of dicarboxylic acids. In skin care, it is most commonly used to treat acne. However, azelaic acid also reduces melanin production by inhibiting (largely indirectly) the enzyme tyrosinase. It also suppresses the proliferation of abnormal melanin producing cells (melanocytes) by reducing the rate of DNA synthesis. Azelaic acid has been used to treat melasma, lentigo maligna and other hyperpigmentation problems. Azelaic acid also inhibits cellular oxidative metabolism and scavenges free radicals, thus providing anti-inflammatory effects.
